To provide transparency and realize synergies, the PanACEA partners have collaborated to implement a plan for capacity development. PanACEA has conducted initial assessment of each proposed site’s requirements to attain or maintain ICH-GCP or GCLP standards and to establish recruitment capacity required for the proposed clinical trials. During the annual meetings of the PanACEA Consortium Board, the site PIs have then together developed a consortium-wide strategy and budget for capacity development. Based on the plan developed by the PanACEA Consortium, funds have been allocated to sites, with budgets specified for each capacity-building activity. The PanACEA team has been monitoring on an ongoing basis both the expenditure of allocated funds by the sites and their progress toward achieving their targets.

Major infrastructure upgrades include the following:


aurum_instituteAurum Institute for Health Research, Tembisa Hospital Site

  • New facility built using prefabricated buildings
  • New pharmacy including airconditioners
  • Energy-saving infra-red elcetric heaters and UV germicidal lights in the participant waiting areas
  • Fully equipped emergency room
  • State of the art alarm and access control system
  • Research lab including bio safety cabinet, centrifuge, -80°C and -20°C freezers, liquid nitrogen storage tanks


Makarere University, Mulago Hospital

  • The floors and verandahs were done with terrazzo finishing for both wards, and washrooms.
  • Ceiling boards were removed and a mild steel louvered roof vent was fixed on both sides of the ward.
  • All doors on the ward were changed. The entrance to the wards (male & female sides) was fixed with flash double doors with a viewing glass and the clinic was fixed with a solid ordinary door with a viewing glass.
  • An extra room was created on the male side of the ward for the nurses.
  • Toilet walls were fixed with tiles and an extra toilet was created on the male side of the ward
  • A wall was built on the toilets on the female side of the ward to prevent outsiders from using the ward washroom.
  • Windows were fixed with coffee tray and mosquito nets


mbeyaMbeya Medical Research Programme

  • Establishment of EBA (colony count) methodology
  • Set up of a functioning ward for GCP-compliant studies requiring overnigth admissions




Kilimanjaro_Clinical_Research_InstituteKilimanjaro Clinical Research Institute

  • Established BSL 2 and BSL3 labs
  • Clinical trial unit equipped to support clinical trials
  • Installation of central server system
  • Refurbishment of bio-repository



lambareneAlbert Schweitzer Hospital – Lambarene (HAS-MRU)

  • Develop laboratory capacity to do MTB culture and sensitivity
  • A NuAire MSC class II was purchased and installed in 2013 Q2 (May)
  • Training for Laboratory staff on the operation of the MGIT 960 for MTB culture
  • Establish a separate TB patients’ reception area/room
  • Negative pressure room still pending

a Health Institute – Bagamoyo and Mwananyamala

Mwananyamala TB clinic is complete and is fully operational with current TB MAMS study running smoothly. The clinic is equipped with GeneXpert machine, a -80°C freezer, x-ray digitizer and centrifuge machine.

  • BSL2 is already operational. BSL3 is expected to be complete by the year 2013.
  • Refurbishment of the TB clinic at the Mwananyamala Hospital in Dar es Salaam