We are faced with a global pandemic of tuberculosis and new tools to control this disease are needed urgently. We believe that new and old optimized drugs are central to any control strategy and the fastest route to tuberculosis elimination.
Latest news
PanACEA General Assembly
Monday 9th of December the PanACEA General Assembly (GA) met again for its quarterly assembly to report and discuss the progress of the project. The first phase of the BTZ043 trial has started at the end of November at UCTLI and TASK Applied Science. Preparations for the SUDOCU and PHENORIF trials are progressing. Next time,…
Press Release
The new drug substance BTZ043 is being tested on patients for the first time in a Phase II study performed by the PanACEA consortium. The trial is carried out in Cape Town, South Africa at TASK Applied Science Clinical Research Centre and the University of Cape Town Lung Institute (UCTLI). The study is funded by…
PanACEA adds SUDOCU and PHENORIF trials to portfolio
We are pleased to announce that our consortium has added to trials two its portfolio. The SUDOCU and PHENORIF trials replace the Q203 study that was initially planned in the Grant Agreement. The trials will take place in South Africa and Tanzania in 2020. Having established the maximum tolerated dose of rifampicin in the HIGHRIF…
Read more PanACEA adds SUDOCU and PHENORIF trials to portfolio
Maximum tolerated dose of rifampicin identified
The PanACEA HIGHRIF trial that started in the first phase of PanACEA has continued in the current programme and has succesfully come to an end. The maximum tolerated dose of rifampicin was identified at 40mg/kg. Martin Boeree recently presented the results at The 50th Union World Conference on Lung Health in Hyderabad, India. The publication…
First patients enrolled in BTZ043 trial
PanACEA has enrolled the first patients in the first cohort of the BTZ043 trial. BTZ043 is a new compound with activity against tuberculosis. The trial is a phase Ib/IIa study to assess the safety and tolerability of BTZ043 and to evaluate bactericidal activity of different doses. The trial takes place at the University of Cape…