On October 26th, 2016 The Lancet Infectious Diseases published the most recent findings from the multi-arm, multi stage tuberculosis (MAMS-TB) trial of the PanACEA consortium. The MAMS-TB trial investigated four new potential regimens for the treatment of tuberculosis. Trial results show that the highest rifampicin dose tested (35 mg/kg) is safe and reduces the time…
The preparations for PanACEA II have been in full swing with a meeting of a large part of the consortium in Liverpool. On October 26th 2016, the international group of partners met again to share thoughts and ideas about the continuation of PanACEA. Several presentations were held, results were shared and organisational issues were discussed.…
Press release – Nijmegen, Netherlands / Munich, Germany February 26th 2015: At the annual Conference on Retroviruses and Opportunistic Infections (CROI), PanACEA, the Pan-African Consortium for the Evaluation of Antituberculosis Antibiotics, presented the results of its most recent phase IIb study (MAMS-TB-01). The most exciting finding from the study is that high-dose rifampicin results in…
Read more PanACEA MAMS-TB-01 finds high-dose rifampicin may help shorten TB treatment
On January 25 – 28 the final PanACEA I meeting was held in Alpbach, Austria. PanACEA members of 11 countries (Belgium, Gabon, Germany, Great Britain, Kenya, Mozambique South Africa, Tanzania, The Netherlands, Uganda, and Zambia) attended the meeting. The newest results of the clinical studies, master and PhD studies and capacity development updates were presented.…
On March 24, 2014, Michael Hoelscher (LMU) presented “Advances in New TB Drug Development”, Tim McHugh (UCL) “Approaches to Monitoring Therapy” and Patrick Phillips (MRC CTU) “Drug Resistance vs. Drug Sensitive Trials “ at the “World TB Day – Reach the 3 Million” in London (www.who.int/campaigns/tb-day/2014/en). This conference, which was a joint venture between University…
Read more PanACEA in “World TB Day 2014 – Reach the 3 Million”
On March 24 (on World TB Day), the MAMS TB-01 Study has completed enrolment ahead of schedule! We congratulate and thank everybody in achieving this goal prior to the target cut-off date of 31 March 2014. 365 patients have been enrolled in 4 South African and 3 Tanzanian sites.
PanACEA, the Pan-African Consortium for the Evaluation of Antituberculosis Antibiotics aims to develop TB regimens that significantly shorten treatment duration, funded by EDCTP. The consortium’s most recent phase IIb study (MAMS-TB-01) uses an innovative adaptive clinical trial design that allows the efficient evaluation of multiple regimens by incorporating interim analyses that allow for the early…
Clinical Ink, in collaboration with PanACEA, received an award for their SureSource platform, a tablet-based system that allows onsite capturing
Read more Best Practices Awards Recognize Excellence in Clinical IT
PanACEA investigators collaborate on comprehensive TB drug development review for Lancet Infectious Diseases special issue for World TB Day. http://www.thelancet.com/journals/laninf/article/PIIS1473-3099%2813%2970328-1/fulltext#
Last fall, the World Health Organization (WHO) published the latest global report on tuberculosis (TB). It provides a comprehensive and up-to-date assessment of the TB epidemic and of the progress made in TB prevention, care and control at global, regional and country level, using data reported by 197 countries and territories that account collectively for…
