PanACEA General Assembly

In the quarterly meeting of the General Assembly of PanACEA on 23rd of September an update was given on the progress of the trials and the capacity development plans. The operational teams and study teams are working hard for the final preparations of the BTZ043 trial that will start in November of 2019. This phase 1A/1B trial will assess the safety/tolerability and bactericidal activity of the novel TB drug BTZ043. Preparations for the SUDOCU study are also well under way. This phase IIB trial is scheduled to start in Q2 of 2020 and will assess the optimal dose of sutezolid for larger follow-up studies.

12th International Workshop on Clinical Pharmacology of Tuberculosis Drugs

On Tuesday 10th of September the 12th edition of the International Workshop on Pharmacology of Tuberculosis Drugs took place in London. The annual platform brings together experts to share the latest findings in the field of TB clinical pharmacology. From this perspective, Lindsey te Brake presented the PK findings of the PanACEAII HR1 trial. Elin Svensson gave a presentation on exposures, treatment response and biomarkers, also a key theme of the PanACEAII project.


The yearly INTERTB symposium, organised by dr. Amina Jindani, was held in London on Monday 9th of September. Martin Boeree presented the results of the PanACEAII HR1 trial and opened the discussion on the optimal dose of rifampicin. Other speakers were, amongst others, consortium members Patrick Phillips, Timothy McHugh and Gerry Davies.

Dr. Celso Khosa

Celso Khosa is the scientific director of Centro de Investigação e Treino em Saúde da Polana Caniço (CISPOC), Instituto Nacional de Saúde Mozambique (INS) since 2018 and he is responsible for the daily activities of PanACEA II in Mozambique.

Dr. Khosa has been a medical doctor and researcher at INS-CISPOC since 2013, leading the TB research program, implementing observational studies and clinical trials in TB therapeutics and diagnostics in adult and paediatric population. He is a last year PhD candidate in Medical Research / International Health at the University of Munich. Dr. Khosa is currently the Principal Investigator in several TB studies, including clinical trials for new drugs in TB and HIV treatment.

His main research interest includes tuberculosis, HIV and Comorbidities associated with HIV.

Dr Julia Dreisbach

Dr. Julia Dreisbach, a veterinary doctor, led the preclinical development of BTZ-043 and now acts as clinical project manager in the BTZ-043 Multiple Ascending Dose Study in Patients.

She coordinates in parallel all non-clinical activities like for example long term toxicity studies in animals, cold- and radiolabeled ADME studies in animals and the development of a suitable drug formulation for BTZ-043

Dr Susanne Schultz

Dr Susanne Schultz studied medicine at the University of Hamburg and is a qualified consultant for general medicine and emergency medicine. From 2007 until 2016 she was living and working as a general practitioner in the UK, the Netherlands and Turkey and completed an MSc in Clinical Trial Management at the Beuth Technical University, Berlin. During these years Dr Schultz supported charities in Kenya as a clinician and medical advisor. She joined the University of Munich in 2017 as clinical investigator and clinical trial coordinator, managing a multi-center trial in the Department for General and Family Medicine. In 2018 she took on a position as sponsor medical expert in the Division of Infectious Diseases and Tropical Medicine, where Dr Schultz is currently working several Phase II TB studies within PanACEA and other projects in Africa.

Larissa Hoffmann

Larissa completed her studies in nutritional science in 2009 and graduated with majors in nutritional medicine. Thereafter, she started her career in the field of clinical trials as a study coordinator for regulated clinical trials in an in-patient clinical setting. After several years she took up a position as a clinical operations manager in a biopharmaceutical start-up company gearing towards the development of immune evasion vaccines and later joined Hipp GmbH & Co. KG as a clinical project manager for the management of clinical studies on infant formulas. During those years she completed several trainings in ICH-GCP, study management and medical writing. In 2018, Larissa joined the Division of Infectious Diseases and Tropical Medicine at the LMU Munich and acts as a clinical project manager for PanACEA TB trials in the office in Munich and in the field.

General Assembly Teleconference September

Every 3 months the PanACEA consortium is meeting via teleconference to update each other on the progress of the trials and the capacity development program. On September the 10th 2018 the partners assembled again.

The so-called Expertise Cores can finally carry out their plans. They have started to purchase data management systems and statistical software.

The PanACEA Postgraduate Program is facilitated by the Expertise Cores and we are excited that applications have been opened.

PanACEA is also gearing up for the upcoming Ninth EDCTP Forum and The 49th Union World Conference on Lung Health.

DEADLINE EXTENSION: Submission deadline 30 September for PanACEA Postgraduate Programme

We are pleased to announce the opening of our Postgraduate programme, which will offer candidates a unique opportunity to support PanACEA objectives and obtain a research degree. The research programmes will be sponsored by expertise core and other affiliated resources. Candidates will be matched to appropriate projects based on their scientific interests, experience and acumen.

To apply, the Postgraduate Application Form (below or click here) must be submitted, which consists of two parts (Part A and B). First, candidates must fill out Part A of the form. In Part B a statement of support must be supplied by a principal investigator (PI)/other referee.*

Closing date for submission: Sunday 30th September 2018 at 23:59 Greenwich Median Time (UK Time)

For further information or assistance, please contact Prof Tim McHugh ( and or Lavinia Rodney (

Upon application, the principal investigator (PI)/other referee will be contacted via email to also provide projects for this scheme (Part C)



Postgraduate Application Form

Part A: Applicant to fill out
Part B: Principal investigator (PI)/other referee


New EDCTP Project Officer

As of June the PanACEA consortium welcomes Jean Marie Habarugira as the new EDCTP Project Officer. At the General Assembly meeting on June 11th the consortium had the first opportunity to get acquainted with him and an official visit will follow. Jean Marie Habarugira has been working for the EDCTP as Project Officer since 2010. To get to know him better, go to:

Jean Marie Habarugira is replacing Monique Rijks-Surette, who is leaving EDCTP to start a position at Johnson & Johnson. We enjoyed the pleasant cooperation and wish her all the best in the new challenges ahead.