PanACEA adds SUDOCU and PHENORIF trials to portfolio

We are pleased to announce that our consortium has added two trials to its portfolio. The SUDOCU and PHENORIF trials replace the Q203 study that was initially planned in the Grant Agreement. The trials will take place in South Africa and Tanzania in 2020.

Having established the maximum tolerated dose of rifampicin in the HIGHRIF trial, the purpose of the PHENORIF study is to further investigate the interaction potential of the higher dosages with a so-called metabolic phenotyping design. This method is a new concept in the PanACEA trial portfolio.

The objective of the SUDOCU trial is to identify the optimal dose of sutezolid in order to advance it into the novel STEPIIC design of PanACEA in which several combinations regimens are evaluated.